Mandatory COVID-19 testing for international travelers

The U.S. Centers for Disease Control and Prevention (CDC) recently issued a directive requiring COVID-19 testing for all inbound international travelers 2 years of age and older. This requirement took effect Jan. 26, 2021, and applies to both foreign nationals and U.S. residents.

The testing must occur no more than three days before a flight departs, and travelers need to provide proof of the negative result or documentation of having recovered from COVID-19 to the airline before boarding.

If you have had a positive viral test in the past three months and have met the criteria to end isolation, you must travel with a copy of your positive test result and a letter from your doctor or health department that states you have been cleared for travel.

You do not need to quarantine upon arrival to Mayo Clinic. Mayo Clinic's policy continues to be that COVID-19 testing offers sufficient screening for COVID-19 for campus visitors.

For further information on the U.S. policy, visit:

Before coming to a Mayo Clinic campus, please review our current COVID-19 policies and information, including our mandatory mask policy.